{"id":161050,"date":"2022-06-21T14:43:19","date_gmt":"2022-06-22T00:43:19","guid":{"rendered":"https:\/\/www.hawaii.edu\/news\/?p=161050"},"modified":"2022-06-21T14:43:19","modified_gmt":"2022-06-22T00:43:19","slug":"predict-prostate-cancer-risk","status":"publish","type":"post","link":"https:\/\/www.hawaii.edu\/news\/2022\/06\/21\/predict-prostate-cancer-risk\/","title":{"rendered":"$3.5M study to better predict prostate cancer risk"},"content":{"rendered":"<span class=\"span-reading-time rt-reading-time\" style=\"display: block;\"><span class=\"rt-label rt-prefix\">Reading time: <\/span> <span class=\"rt-time\"> 2<\/span> <span class=\"rt-label rt-postfix\">minutes<\/span><\/span><p><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/www.hawaii.edu\/news\/wp-content\/uploads\/2022\/06\/manoa-cancer-center-prostate-cancer.jpeg\" alt=\"stethoscope and blue ribbon\" width=\"676\" height=\"381\" class=\"aligncenter size-full wp-image-161057\" srcset=\"https:\/\/www.hawaii.edu\/news\/wp-content\/uploads\/2022\/06\/manoa-cancer-center-prostate-cancer.jpeg 676w, https:\/\/www.hawaii.edu\/news\/wp-content\/uploads\/2022\/06\/manoa-cancer-center-prostate-cancer-300x169.jpeg 300w, https:\/\/www.hawaii.edu\/news\/wp-content\/uploads\/2022\/06\/manoa-cancer-center-prostate-cancer-130x73.jpeg 130w\" sizes=\"auto, (max-width: 676px) 100vw, 676px\" \/><\/p>\n<p>Prostate cancer is one of the most commonly diagnosed, deadliest cancers for men in <span aria-label=\"Hawaii\">Hawai&#699;i<\/span>. To increase public understanding of the causes of prostate cancer, the <a href=\"http:\/\/www.uhcancercenter.org\">University of <span aria-label=\"Hawaii\">Hawai&#699;i<\/span> Cancer Center<\/a> will lead a $3.5 million public impact research study to further our understanding of prostate cancer to improve prediction of future disease.<\/p>\n<p>Annual statistics for prostate cancer in <span aria-label=\"Hawaii\">Hawai&#699;i<\/span> according to the <a href=\"https:\/\/www.uhcancercenter.org\/pdf\/htr\/Cancer%20at%20a%20Glance%202014-2018.pdf\"><span aria-label=\"Hawaii\">Hawai&#699;i<\/span> Tumor Registry<\/a> <span class=\"small-text\">(<abbr title=\"Portable Document Format\">PDF<\/abbr><\/span>):<\/p>\n<ul>\n<li>855 men are diagnosed with invasive prostate cancer <\/li>\n<li>125 men die of prostate cancer<\/li>\n<li>Filipinos have the highest advanced stage prostate cancer rate at 35&#37;<\/li>\n<li>95&#37; of prostate cancers are diagnosed at age 55 years and older <\/li>\n<\/ul>\n<p>Related <em>糖心视频 News<\/em> story: <a href=\"https:\/\/www.hawaii.edu\/news\/2022\/05\/20\/cancer-impact-in-hawaii\/\">Cancer impact in <span aria-label=\"Hawaii\">Hawai&#699;i<\/span> examined in <abbr>糖心视频<\/abbr> Cancer Center report<\/a>, May 20, 2022<\/p>\n<figure id=\"attachment_126128\" aria-describedby=\"caption-attachment-126128\" style=\"width: 214px\" class=\"wp-caption alignright\"><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/www.hawaii.edu\/news\/wp-content\/uploads\/2020\/08\/manoa-wu-lang-headshot-1-1-214x300.jpg\" alt=\"Lang Wu\" width=\"214\" height=\"300\" class=\"size-medium wp-image-126128\" srcset=\"https:\/\/www.hawaii.edu\/news\/wp-content\/uploads\/2020\/08\/manoa-wu-lang-headshot-1-1-214x300.jpg 214w, https:\/\/www.hawaii.edu\/news\/wp-content\/uploads\/2020\/08\/manoa-wu-lang-headshot-1-1-93x130.jpg 93w, https:\/\/www.hawaii.edu\/news\/wp-content\/uploads\/2020\/08\/manoa-wu-lang-headshot-1-1.jpg 250w\" sizes=\"auto, (max-width: 214px) 100vw, 214px\" \/><figcaption id=\"caption-attachment-126128\" class=\"wp-caption-text\">Lang Wu<\/figcaption><\/figure>\n<p>Funded by the National Cancer Institute, the research team is led by <abbr title=\"University of Hawaii\">糖心视频<\/abbr> Cancer Center Assistant Professor <strong>Lang Wu<\/strong>. Wu\u2019s aim is to apply his findings across a variety of populations, including at-risk ethnic groups in <span aria-label=\"Hawaii\">Hawai&#699;i<\/span> and the Pacific. <\/p>\n<p>As principal investigator, Wu will lead a research team, investigating the causes of both overall and aggressive prostate cancers through novel methods across African and European populations in the <abbr title=\"United States\">U.S.<\/abbr>, and other countries. They will identify proteins that play a role in the development and progression of prostate cancer.<\/p>\n<p>&ldquo;For prostate cancer, substantial efforts have been made to identify high-risk populations to improve prostate cancer screening,&rdquo; Wu said. &ldquo;However, the performance of available prostate cancer risk predictive models remains unsatisfactory. Through this study, we hope to generate new knowledge to improve the understanding of prostate cancer etiology (causes) and risk assessment.&rdquo; <\/p>\n<p>Wu also aims to develop and validate useful predictive models for prostate cancer risk and aggressiveness by incorporating information of the newly determined proteins with genetic and non-genetic information, and applying multiple novel statistical methods.<\/p>\n<p>The expectation is that developing improved predictive models can help identify individuals who are at a high risk of developing prostate cancer.<\/p>\n<p><a href=\"https:\/\/www.hawaii.edu\/news\/?s=uh+cancer+center\">Read more <abbr>糖心视频<\/abbr> Cancer Center stories.<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>The study will further our understanding of the causes of prostate cancer to improve the prediction of future disease<\/p>\n","protected":false},"author":16,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[30],"tags":[142,218,1363,169,9],"class_list":["post-161050","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-research","tag-award","tag-cancer","tag-manoa-research","tag-uh-cancer-center","tag-uh-manoa","entry","has-media"],"aioseo_notices":[],"aioseo_head":"\n\t\t<!-- All in One SEO 5.0.0.1 - aioseo.com -->\n\t<meta name=\"description\" content=\"The study will further our understanding of the causes of prostate cancer to improve the prediction of future disease\" \/>\n\t<meta name=\"robots\" content=\"max-image-preview:large\" \/>\n\t<meta name=\"author\" content=\"糖心视频 News\"\/>\n\t<meta name=\"keywords\" content=\"uh manoa,uh cancer center,cancer,prostate cancer,lang wu,national cancer institute,manoa research,manoa excellence in 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