{"id":80584,"date":"2018-06-04T10:25:36","date_gmt":"2018-06-04T20:25:36","guid":{"rendered":"https:\/\/www.hawaii.edu\/news\/?p=80584"},"modified":"2020-03-13T15:11:23","modified_gmt":"2020-03-14T01:11:23","slug":"chronic-hiv-complications-study-award","status":"publish","type":"post","link":"https:\/\/www.hawaii.edu\/news\/2018\/06\/04\/chronic-hiv-complications-study-award\/","title":{"rendered":"<abbr title=\"University of Hawaii\">ÌÇÐÄÊÓƵ<\/abbr> researcher honored for study of chronic <abbr>HIV<\/abbr> complications"},"content":{"rendered":"<span class=\"span-reading-time rt-reading-time\" style=\"display: block;\"><span class=\"rt-label rt-prefix\">Reading time: <\/span> <span class=\"rt-time\"> &lt; 1<\/span> <span class=\"rt-label rt-postfix\">minute<\/span><\/span><div class=\"responsive-video-wrap\"><iframe loading=\"lazy\" width=\"676\" height=\"380\" src=\"https:\/\/www.youtube.com\/embed\/irPalQbbEt8?rel=0&amp;showinfo=0\" frameborder=\"0\" title=\"YouTube video player\" allowfullscreen><\/iframe><\/div>\n<figure id=\"attachment_80623\" aria-describedby=\"caption-attachment-80623\" style=\"width: 250px\" class=\"wp-caption alignright\"><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/www.hawaii.edu\/news\/wp-content\/uploads\/2018\/06\/manoa-jabsom-mitchell-b.jpg\" alt=\"\" width=\"250\" height=\"350\" class=\"size-full wp-image-80623\" srcset=\"https:\/\/www.hawaii.edu\/news\/wp-content\/uploads\/2018\/06\/manoa-jabsom-mitchell-b.jpg 250w, https:\/\/www.hawaii.edu\/news\/wp-content\/uploads\/2018\/06\/manoa-jabsom-mitchell-b-214x300.jpg 214w\" sizes=\"auto, (max-width: 250px) 100vw, 250px\" \/><figcaption id=\"caption-attachment-80623\" class=\"wp-caption-text\">Brooks Ikaikaokekai Mitchell<\/figcaption><\/figure>\n<p>A <a href=\"https:\/\/manoa.hawaii.edu\/\">University of <span aria-label=\"Hawaii\">Hawai&#699;i<\/span> at M\u0101noa<\/a> researcher is investigating why people with human immunodeficiency virus (<abbr>HIV<\/abbr>) are living longer with antiretroviral treatment yet experiencing more chronic complications as they age. <a href=\"http:\/\/manoa.hawaii.edu\/tropicalmedicine\/?page_id=2790\"><strong>Brooks Ikaikaokekai Mitchell<\/strong><\/a> was awarded the 2018 Koenig Foundation Award in Medicine by the <a href=\"https:\/\/honolulu.arcsfoundation.org\/\">Achievement Rewards for College Scientists Foundation Honolulu Chapter<\/a>.<\/p>\n<p>Mitchell, a <abbr title=\"doctoral degree\">PhD<\/abbr> candidate at <abbr>ÌÇÐÄÊÓƵ<\/abbr> M\u0101noa&#8217;s <a href=\"http:\/\/jabsom.hawaii.edu\/\">John A. Burns School of Medicine<\/a> (<abbr>JABSOM<\/abbr>), received the award that includes a $5,000 prize on May 7.<\/p>\n<p>At <abbr>JABSOM<\/abbr>, Mitchell is part of a team at the <a href=\"http:\/\/manoa.hawaii.edu\/hicfa\/\"><span aria-label=\"Hawaii\">Hawai&#699;i<\/span> Center for <abbr title=\"acquired immune deficiency syndrome\">AIDS<\/abbr><\/a> that is examining why those with <abbr>HIV<\/abbr> suffer earlier from diseases related to aging than those who are not infected with <abbr>HIV<\/abbr>.<\/p>\n<p>&ldquo;<abbr>HIV<\/abbr> has been around for decades, but there is still a lot of work to be done,&rdquo; said Mitchell. &ldquo;This recognition of the work that our group is doing is an honor.&rdquo;<\/p>\n<h2>About his research<\/h2>\n<p>&ldquo;One of the projects that I&#8217;ve been working on is looking at lymph node fibrosis,&rdquo; said Mitchell. &ldquo;We excised the lymph nodes from 10 volunteers and conducted various immunoassays to understand the immunological mechanisms that may be driving fibrosis within these tissues.&rdquo;<\/p>\n<p>Fibrosis is not normal and interferes with the functionality of the tissue, Mitchell explains.<\/p>\n<p>&ldquo;Lymph nodes are important in the immune response, so when you have a lot of collagen deposits&#8212;which is the definition of fibrosis&#8212;occurring within these tissues, it interferes with normal immune processes that may result in persistent inflammation,&rdquo; he said. &ldquo;It may be a reason why we see a lot of chronic complications within our (<abbr>HIV<\/abbr>) patients.&rdquo;<\/p>\n<p>See the <a href=\"http:\/\/jabsom.hawaii.edu\/hawai%ca%bbi-center-for-aids-scientist-brooks-mitchell-earns-koenig-foundation-award-in-medicine\/\">full story<\/a> on the <abbr>JABSOM<\/abbr> website.<\/p>\n<p><em>&#8212;By Tina Shelton<\/em><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Brooks Mitchell was honored with the 2018 Koenig Foundation Award in Medicine from the Achievement Rewards for College Scientists Foundation Honolulu Chapter.<\/p>\n","protected":false},"author":16,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[29],"tags":[598,993,31,9],"class_list":["post-80584","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-people","tag-faculty-recognition","tag-hivaids","tag-john-a-burns-school-of-medicine","tag-uh-manoa","entry","has-media"],"aioseo_notices":[],"jetpack_featured_media_url":"","_links":{"self":[{"href":"https:\/\/www.hawaii.edu\/news\/wp-json\/wp\/v2\/posts\/80584","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.hawaii.edu\/news\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.hawaii.edu\/news\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.hawaii.edu\/news\/wp-json\/wp\/v2\/users\/16"}],"replies":[{"embeddable":true,"href":"https:\/\/www.hawaii.edu\/news\/wp-json\/wp\/v2\/comments?post=80584"}],"version-history":[{"count":13,"href":"https:\/\/www.hawaii.edu\/news\/wp-json\/wp\/v2\/posts\/80584\/revisions"}],"predecessor-version":[{"id":113700,"href":"https:\/\/www.hawaii.edu\/news\/wp-json\/wp\/v2\/posts\/80584\/revisions\/113700"}],"wp:attachment":[{"href":"https:\/\/www.hawaii.edu\/news\/wp-json\/wp\/v2\/media?parent=80584"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.hawaii.edu\/news\/wp-json\/wp\/v2\/categories?post=80584"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.hawaii.edu\/news\/wp-json\/wp\/v2\/tags?post=80584"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}