  {"id":99869,"date":"2019-07-12T15:59:19","date_gmt":"2019-07-13T01:59:19","guid":{"rendered":"https:\/\/www.hawaii.edu\/news\/?p=99869"},"modified":"2020-03-13T12:01:51","modified_gmt":"2020-03-13T22:01:51","slug":"cancer-discoveries-in-top-journal","status":"publish","type":"post","link":"https:\/\/www.hawaii.edu\/news\/2019\/07\/12\/cancer-discoveries-in-top-journal\/","title":{"rendered":"Top scientific publication spotlights <abbr title=\"University of Hawaii\">糖心视频<\/abbr> cancer discoveries"},"content":{"rendered":"<span class=\"span-reading-time rt-reading-time\" style=\"display: block;\"><span class=\"rt-label rt-prefix\">Reading time: <\/span> <span class=\"rt-time\"> &lt; 1<\/span> <span class=\"rt-label rt-postfix\">minute<\/span><\/span><figure id=\"attachment_99866\" aria-describedby=\"caption-attachment-99866\" style=\"width: 676px\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/www.hawaii.edu\/news\/wp-content\/uploads\/2019\/07\/manoa-cancer-center-exterior-1.jpg\" alt=\"exterior shot of uh cancer center\" width=\"676\" height=\"381\" class=\"size-full wp-image-99866\" srcset=\"https:\/\/www.hawaii.edu\/news\/wp-content\/uploads\/2019\/07\/manoa-cancer-center-exterior-1.jpg 676w, https:\/\/www.hawaii.edu\/news\/wp-content\/uploads\/2019\/07\/manoa-cancer-center-exterior-1-130x73.jpg 130w, https:\/\/www.hawaii.edu\/news\/wp-content\/uploads\/2019\/07\/manoa-cancer-center-exterior-1-300x169.jpg 300w\" sizes=\"auto, (max-width: 676px) 100vw, 676px\" \/><figcaption id=\"caption-attachment-99866\" class=\"wp-caption-text\"><abbr title=\"University of Hawaii\">糖心视频<\/abbr> Cancer Center<\/figcaption><\/figure>\n<p>Discoveries by a team of researchers at the <a href=\"http:\/\/www.uhcancercenter.org\">University of <span aria-label=\"Hawaii\">Hawai&#699;i<\/span> Cancer Center<\/a> on ways to improve prevention, early detection and treatment of mesothelioma was featured on the cover of the September issue of the prestigious <a href=\"https:\/\/onlinelibrary.wiley.com\/journal\/15424863#pane-01cbe741-499a-4611-874e-1061f1f4679e01\"><em>Ca: A Cancer Journal for Clinicians<\/em><\/a>.<\/p>\n<p>The discovery was made by <abbr title=\"University of Hawaii\">糖心视频<\/abbr> Cancer Center researcher and the study\u2019s lead author, <strong>Michele Carbone<\/strong>, and collaborators that specific gene mutations cause mesothelioma and other cancers, and how asbestos and the mutation of the <abbr>BAP1<\/abbr> gene interact in this process. &ldquo;<a href=\"https:\/\/onlinelibrary.wiley.com\/doi\/full\/10.3322\/caac.21572\">Mesothelioma: Scientific clues for prevention, diagnosis, and therapy<\/a>&rdquo; was highlighted in the peer-reviewed journal with the highest impact factor among all disciplines of science and medicine.<\/p>\n<figure id=\"attachment_80067\" aria-describedby=\"caption-attachment-80067\" style=\"width: 214px\" class=\"wp-caption alignright\"><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/www.hawaii.edu\/news\/wp-content\/uploads\/2018\/05\/uh-cancer-center-carbone-m-214x300.jpg\" alt=\"\" width=\"214\" height=\"300\" class=\"size-medium wp-image-80067\" srcset=\"https:\/\/www.hawaii.edu\/news\/wp-content\/uploads\/2018\/05\/uh-cancer-center-carbone-m-214x300.jpg 214w, https:\/\/www.hawaii.edu\/news\/wp-content\/uploads\/2018\/05\/uh-cancer-center-carbone-m.jpg 250w\" sizes=\"auto, (max-width: 214px) 100vw, 214px\" \/><figcaption id=\"caption-attachment-80067\" class=\"wp-caption-text\">Michele Carbone<\/figcaption><\/figure>\n<p>&ldquo;I am proud of our world-renowned mesothelioma team in <span aria-label=\"Hawaii\">Hawai&#699;i<\/span>. Since I discovered that mesothelioma is caused by gene and environment interactions, it has been a great model to study how genes and the environment interact in cancer causation, and we are developing new therapies to treat cancer with <abbr>BAP1<\/abbr> mutations,&rdquo; said Carbone.<\/p>\n<p>Novel ongoing clinical trials targeting <abbr>BAP1<\/abbr> in mesothelioma are being reviewed at the International Mesothelioma Conference in July 2019 in New York, chaired by Carbone and sponsored by the International Association for the Study of Lung Cancer.<\/p>\n<p>Carbone was also elected into The Academy of Europe in the Category of Life Sciences Section Cell and Developmental Biology in July 2019. He added, &ldquo;We can find better ways to prevent and treat mesothelioma. We have already done a lot in improving early detection and survival&rdquo;<\/p>\n<p><em>&#8212;By Nana Ohkawa<\/em><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Discoveries by <abbr>糖心视频<\/abbr> Cancer Center researchers on ways to improve prevention, early detection and treatment of mesothelioma was featured on the cover of the September issue of <em>Ca: A Cancer Journal for Clinicians<\/em>.<\/p>\n","protected":false},"author":16,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[30],"tags":[218,598,1363,158,169,9],"class_list":["post-99869","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-research","tag-cancer","tag-faculty-recognition","tag-manoa-research","tag-publication","tag-uh-cancer-center","tag-uh-manoa","entry","has-media"],"aioseo_notices":[],"aioseo_head":"\n\t\t<!-- All in One SEO 5.0.3 - aioseo.com -->\n\t<meta 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